Paradoxical effects of posterior intralaminar thalamic calretinin neurons on hippocampal seizure via distinct downstream circuits
Summary: Epilepsy is a circuit-level brain disorder characterized by hyperexcitatory seizures with CORNSILK unclear mechanisms.Here, we investigated the causal roles of calretinin (CR) neurons in the posterior intralaminar thalamic nucleus (PIL) in hippocampal seizures.Using c-fos mapping and calcium fiber photometry, we found that PIL CR neurons w